Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.
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houlinlin
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by houlinlin » Sun Nov 04, 2007 2:04 am
I am confused by the differences of ATP and ATPS appeared in an article.would anyone show me what are the differences between them ?
Thanks very much!

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Katy_Bobbles
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by Katy_Bobbles » Sun Nov 04, 2007 11:45 am
I assume the ATP S is ATP synthase, the enzyme which catalyses the addition of a phosphate group to ADP to make ATP
Hope that makes sense and it is what the S stood for

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blcr11
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by blcr11 » Sun Nov 04, 2007 3:04 pm
...or ATP-[gamma]-S? There was that little box which usually means some sort of non-displayable character in the font set. Anyway, ATP-gamma-S is an ATP analogue in which the gamma-phosphate atom is replaced by a sulfur atom, if that's what you were wondering. The compound binds like ATP, but doesn't react like ATP.
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houlinlin
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by houlinlin » Mon Nov 05, 2007 12:43 am
Thanks for your replys.I am sure I have got the answer.
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pluto
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by pluto » Thu Nov 15, 2007 6:57 am
to clarify on the post about ATP[gamma]S. When the gamma-P is replaced with an S, then that bond can no longer be cleaved (i.e. ATP->ADP). Thus, people use the "non hydrolyzable" form of nucleotides to study enzyme activity when you don't have to worry about substrate depletion
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