Search found 2 matches

by SoyeongPark
Fri Mar 19, 2010 9:28 am
Forum: Molecular Biology
Topic: Restriction enzyme-enzyme specificity
Replies: 0
Views: 2046

Restriction enzyme-enzyme specificity

Hi, I was studying about restriction enzyme and I know that restriction enzyme recognize its substrate by recognizing distortion of the recognition site. And then the textbook said that: "The distortion of the substrate and the subsequent binding of the magnesium ion account for the catalytic s...
by SoyeongPark
Sat Mar 13, 2010 10:23 am
Forum: Molecular Biology
Topic: Why does negative supercoiling favor unwinding?
Replies: 1
Views: 1653

Why does negative supercoiling favor unwinding?

Hi,

I was just studying about RNA polymerase and am a little bit confused because of this:
"Negative supercoiling of circular DNA favors the transcription of genes because it facilitates unwinding."
Why does negative supercoiling favor unwinding?
Please help me

Thank you in advance :D