Search found 7 matches

by carbonp
Mon Nov 16, 2009 10:34 pm
Forum: General Discussion
Topic: Difference between spectrocopy
Replies: 3
Views: 9555

Difference between spectrocopy

Hi, I am confused between Ultraviolet-visible spectroscopy and fluorescence spectroscopy? Fluorescence is produced when compound absorbs UV light and re-emits visible light. Thus does it mean both are same technique because UV light produces fluorescence. If different what are the specifc difference...
by carbonp
Sun Oct 25, 2009 1:30 pm
Forum: Molecular Biology
Topic: Free drug concentration
Replies: 3
Views: 3316

Sorry its addition of dissociation constant. but formula does not say multiplication of dissociation constant.
by carbonp
Sun Oct 25, 2009 1:20 pm
Forum: Molecular Biology
Topic: Free drug concentration
Replies: 3
Views: 3316

Free drug concentration

If, Free protein = [(Total protein - Total drug -Dissociation constant)] (+/-) under root of (Total protein - Total drug -Dissociation constant)^2 + 4 (dissociation Constant * Total Protein) divided by 2 If Total protein - 0.035 g /microliter, Total drug - 3319.246 x 10^-15 moles/l (Molecular weight...
by carbonp
Tue Oct 20, 2009 6:20 pm
Forum: Molecular Biology
Topic: Drug dissociation constant
Replies: 1
Views: 1542

Drug dissociation constant

1) I need to calculate the concentration represented by one molecule in a animal cell. You should know that typical animal cell is 15 um in diameter and 1 um in thick. You will also remember that avogrado's number is 6 x 10^23. 2) To think about - a rod shaped bacterium is about 1 mm long by 0.5 mm ...
by carbonp
Fri Oct 16, 2009 5:37 pm
Forum: Molecular Biology
Topic: Dilution
Replies: 1
Views: 1103

Dilution

Take 5 small glass test tubes (1-5) and put 1200 μl of distilled water in each. Now add 300 μl of 10 μM atropine to Tube 1, mix well and transfer 300 μl to Tube 2. Mix well and transfer 300 μl to Tube 3. Repeat up to Tube 5. Calculate the atropine concentration in each tube. my question is For first...
by carbonp
Wed Oct 14, 2009 1:37 am
Forum: Molecular Biology
Topic: Solubility and the dissociation constant of the drug?
Replies: 3
Views: 2671

Re: Solubility and the dissociation constant of the drug?

So as the given solubility of the drug is 1.3 g/l and the calculation shows that on administration of drug = 800 grams, only 0.019 gram is present in one liter, which is less than 1.3 g/l, so what does it indicate. I mean to say, what happens if the drug concentration is higher than the given solubi...
by carbonp
Tue Oct 13, 2009 11:50 pm
Forum: Molecular Biology
Topic: Solubility and the dissociation constant of the drug?
Replies: 3
Views: 2671

Solubility and the dissociation constant of the drug?

Hi, I am new to pharmacology, I got one problem task ant its all about the dissociation constant of drug (Kd not pKa), So here is the question, If the drug molecular weight is 225.2 grams/mole and the drug dose is 800 grams per day, considering body weight as 60 kg and 70 % water. How to calculate t...