Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes
Results indicate that CQ should be considered as an HIV-1 therapeutic agent with its influence exerted through a number of mechanisms in vivo, including modulation of the gp120 structure

Rev-dependent lentiviral expression vector
In this report, by inclusion of multiple components of the HIV genome, the authors have constructed a lentiviral expression vector that displays a full dependency on the presence of HIV.

Vaccine for Ebola virus
One of the world's deadliest diseases, caused by the Ebola virus, may finally be preventable

Molecular evolution of influenza A viruses circulated in Fujian Province, China
Fujian Center for Disease Control & Prevention, China, reported the molecular evolution of influenza A (H3N2) viruses in Fujian Province demonstrated some key codons responsible for antigenic drift.

Study provides new understanding of forces behind seasonal flu virus evolution
The new findings should help public health officials more quickly and accurately determine which strains to include in the annual flu vaccine.

Ugandan monkeys harbor evidence of infection with unknown poxvirus
Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus

Potential viral therapy weapon for difficult cancers is safe and effective in study
Study led by Cincinnati Children's proposes further development to advance treatment

A step forward in virology
Trojan horse of viruses revealed

Viruses may play a role in lung cancer development
evidence that common viruses may contribute to the development of lung cancer.

Marijuana component opens the door for virus that causes Kaposi's sarcoma
The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply

HIV is a 'double hit' to the brain
Evidence offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits

St. Jude influenza survey uncovers key differences between bird flu and human flu
Specific mutations linked to immune suppression and viral replications differ between bird and human flu viruses could be used to monitor emerging pandemics

Dengue virus type 2: replication and tropisms in orally infected Aedes aegypti mosquitoes
To be transmitted by its mosquito vector, dengue virus (DENV) must infect midgut epithelial cells, replicate and disseminate into the hemocoel, and finally infect the salivary glands, which is essential for transmission.

New pandemics: HIV and AIDS, HCV and chronic hepatitis, Influenza virus and flu
New pandemics are a serious threat to the health of the entire world. They are essentially of viral origin and spread at large speed.

Molecular analysis of hepatitis B virus "a" determinant in asymptomatic and symptomatic Mexican carriers
Hepatitis B virus (HBV) is a small DNA-containing virus with 4 genes, C, S, X and P.

The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages
With the prospect of another pandemic Influenza fresh in our consciousness, the pathogenic nature of the Influenza A virus and its ability to induce high rates of mortality are ever more pertinent.

Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells
Epigenetic silencing of regulatory genes by aberrant methylation contributes to tumorigenesis.

Quantitative analysis of Nipah virus proteins released as virus-like particles reveals central role for the matrix protein
Nipah virus (NiV) is an emerging paramyxovirus distinguished by its ability to cause fatal disease in both animal and human hosts.

Structure-based engineering of papillomavirus major capsid L1: controlling particle assembly
The outer shell of the papillomavirus particle is comprised of 72 pentamers of the major capsid L1 protein arranged on a T = 7 icosahedral lattice.

Interaction between Bluetongue virus outer capsid protein VP2 and vimentin is necessary for virus egress
In this study it is demonstrated that BTV VP2 associates with vimentin in both virus infected cells and in the absence of other viral proteins.