A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
Stem cell biology takes another exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells

UCLA researchers reprogram normal tissue cells into embryonic stem cells
New technique could allow for cell reprogramming without use of controversial cloning methods

Cancer stem cells can go it alone
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them.

Deakin University research finds rogue cells that could cause spread of breast cancer
Stephanie Lebret completed the study for her PhD at Deakin's Centre for Cellular and Molecular Biology under the supervision of Associate Professor Leigh Ackland.

Findings Offer Clue To How Molecule Can Both Stimulate, Suppress Cell Growth
Scientists are puzzled by the fact that the molecule known as transforming growth factor-beta (TGF-b) generally stops cells from multiplying but at other times promotes cell growth.

Extragenic suppression analysis of TS mutants using Sec61
During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel. Proper folding, degradation, and transport of many polypeptides depend on a diverse set of

New Research Identifies Human Enzyme That Could Be Programmed To Kill Cancer Cells
A new study conducted by scientists at Children's Hospital Oakland Research Institute (CHORI) identifies a specific enzyme that can cause the death of cancer cells.

One signal elicits thousands of answers
Cell signaling mechanisms often transmit information via protein modifications, most importantly the reversible attachment of phosphate, the so-called protein phosphorylation.

Needling Chromosomes Yields Insights Into Cell Division
By impaling individual chromosomes with glass needles one thousandth the diameter of a human hair, a Duke University graduate student has tested their "stickiness" to one another during cell division.

Why Is The Helix Such A Popular Shape? Perhaps Because They Are Nature's Space Savers
Something about nature loves a helix, the ubiquitous spiral shape taken on by DNA and many other molecules found in the cells of living creatures.

Elevated Testosterone Kills Nerve Cells
A Yale School of Medicine study shows for the first time that a high level of testosterone, such as that caused by the use of steroids to increase muscle mass or for replacement therapy, can lead to a catastrophic loss of brain cells.

Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels
These studies were undertaken to test the possibility that phosphorylation by GSK3 is responsible for the S phase specific decline in cyclin D1 levels...

Scratching the (T cell) surface
Using a genome-scale approach to study transcription levels in a human CD8+ T-cell clone, a recent study has suggested that the repertoire of molecules on the surface of T cells is close to being completely characterized.

Qualitative and quantitative characteristics of the extracellular DNA delivered to the nucleus of a living cell
In this work, the authors focused on the research into the behavior of fragmented DNA when it enters the cell compartments of MCF-7 cells.

Good, Bad Blood Cells: They Form Clots, Fight Inflammation
It's a case of miscommunication with catastrophic consequences.

Discovery of the Porosome: revealing the molecular mechanism of secretion and membrane fusion in cells
The discovery of the porosome, its isolation, its structure and dynamics at nm resolution and in real time, its biochemical composition and functional reconstitution, are discussed.

The story of cell secretion: events leading to the discovery of the 'porosome' - the universal secretory machinery in cells
This review outlines the fascinating and exciting journey leading to the discovery of the porosome, ultimately solving one of the most difficult, significant, and fundamental cellular process -cell secretion.

Molecular Machinery and Mechanism of Cell Secretion
A minireview about the universal molecular machinery and mechanism of secretion in cells.

Membrane fusion in cells: molecular machinery and mechanisms
A minireview about the molecular mechanism of SNARE-induced membrane fusion in cells

Scientists Find Molecular Switch That Inhibits Fat Cell Development
Scientists have discovered a molecular switch that controls the formation of fat cells in mice.