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Dictionary » L » Lymph LymphLymph (Science: physiology) The almost colourless fluid that bathes body tissues and is found in the lymphatic vessels that drain the tissues of the fluid that filters across the blood vessel walls from blood. Lymph carries lymphocytes that have entered the lymph nodes from the blood. lymphocytes aid in destroying antigens in which they engulf or they take the antigen to the thrid line of defence ( B and t cells, which are specific). ![]()
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Results from our forumRe: T cell differentiation... biohazard. I think i've got it now: The T cells are produced in the thymus as naive CD4+ and CD8+ cells and then recognise the antigen in the lymph nodes (mainly) but recently there have been RTE's discovered which are not yet CD4 or CD8 positive and differentiate upon activation
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Re:... clarify so the differentiation into subsets can be done in several peripheral tissues including at the site of infection? Yes, the final stages of lymphocyte differentiation take place in the peripheral tissues. Often this peripheral tissue is a secondary lymphoid tissue, such as a lymph node, ...
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T cell differentiation... mentioned above), which determines e.g. the CD4+/CD8+ and A:B/G:D TCR development. The final adjustment, then, happens in the periphery (such as lymph nodes). Apparently RTEs are a relaively recent finding, with Haines et al. (2009) describing a protocol to indentify them, but for a good overall ...
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Re: T cell differentiationSo after they have been activated in the lymph nodes they travel to the thymus where they differentiate and then migrate to infected tissue If anyone knows of a source which provides a good overview of this please let me know. I dont want to ...
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Re: T cell differentiationThanks for the quick reply! However there is one thing which is still confusing me, if they differentiate in the lymph then how are the cytokines which favour one differentiation or another delivered. It's just that in my notes it says NK cells and macrophages can have an effect ...
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