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Lethal mutation

(Science: genetics molecular biology) mutation that eventually results in the death of an organism carrying the mutation. a type of genetic mutation that proves to be deadly. lethal mutations are also possible. As the term implies, the mutations lead to the death of the individual. Death does not have to occur immediately, it may take several months or even years. But if the expected longevity of an individual is significantly reduced, the mutation is considered a lethal mutation.