Home Forum Dictionary Articles Tutorials Books Directory Share your work


Edit page | Page history | Printable version

Dictionary » I » Intron

Intron

Intron

(Science: molecular biology) a noncoding sequence of dna within a gene, that is transcribed into hnrna but is then cut out of the message by rna splicing in the nucleus, leaving a mature mrna that is then translated in the cytoplasm.

introns are poorly conserved and of variable length, but the regions at the ends are self complementary, allowing a hairpin structure to form naturally in the hnrna, this is the cue for removal by rna splicing. Introns are thought to play an important role in allowing rapid evolution of proteins by exon shuffling. Genes may contain as many as 80 introns.

Compare: exon


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Intron: Unusual donor-acceptor splice site (GT-AG)

... what actually happen if the GT-AG sites were intervened with unusual junction sequences (before GT/after AG), for eg: 1. gcgcgggc T GT GCGTC...INTRON...C AG TT gatgc [exon- INTRON -exon] 2. tgaatcagcagg GG GT GCGTC...INTRON...C AG A aagtttatggg [exon- INTRON -exon] Is it because of intron frameshifting/intron ...

See entire post
by molecular09
Wed Jul 01, 2009 8:52 am
 
Forum: Molecular Biology
Topic: Intron: Unusual donor-acceptor splice site (GT-AG)
Replies: 0
Views: 224

Re: Help with sequencing DNA.

... might be a pre-mRNA splicing event within the sequence that produces the mature mRNA strand. If so, the DNA sequence would be interrupted by an intron. If there is no splicing event, the mRNA sequence is the same as the sense sequence. Be careful, this is not how the sequences were shown in ...

See entire post
by jonmoulton
Mon Jun 29, 2009 4:47 pm
 
Forum: Molecular Biology
Topic: Help with sequencing DNA.
Replies: 3
Views: 189

Re: Retained Intron through Translation

When an intron is included, you are likely to have a stop codon in-frame in the intron. This triggers nonsense-mediated decay of the mRNA. Frameshifting downstream sequence by including an intron with a number of bases not evenly ...

See entire post
by jonmoulton
Tue May 05, 2009 11:52 pm
 
Forum: Genetics
Topic: Retained Intron through Translation
Replies: 1
Views: 443

Retained Intron through Translation

What happens to a protein sequence when an intron is not spliced out in the maturation of an mRNA strand? All I could come up with was that you would get a garbage protein with incorrect amino acids once the ribosome got to the intron. I guess ...

See entire post
by cgh24
Tue May 05, 2009 9:55 pm
 
Forum: Genetics
Topic: Retained Intron through Translation
Replies: 1
Views: 443

Re: nucleotides

The coding strand of the DNA is made up of introns (non-coding parts) and exons (coding parts). when the mRNA is transcripted from the DNA it includes all the corresponding parts (both the introns and exons) but then the mRNA is spliced, which ...

See entire post
by menu
Wed Apr 15, 2009 6:06 am
 
Forum: Genetics
Topic: nucleotides
Replies: 1
Views: 422
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 2,866 times. 
What links here | Related changes | Permanent link