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Initiation

Initiation

1. The first stage of tumour induction by a carcinogen; subtle alteration of cells by exposure to a carcinogenic agent so that they are likely to form a tumour upon subsequent exposure to a promoting agent (promotion).

2. Starting point of replication or translation in macromolecule biosynthesis.

3. Start of chemical or enzymatic reaction.


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multiple initiation sites.

... are being asked here. Not sure if chromatin modeling or epigenetics fall into this category yet :) And could you please specify as to how multiple initiation sites actually enhance the accuracy of replication? As far as I know, intitiation sites are realted to gene expression (i.e. the starting ...

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by biohazard
Thu Aug 20, 2009 7:11 am
 
Forum: Cell Biology
Topic: multiple initiation sites.
Replies: 5
Views: 98

multiple initiation sites.

Hmmh, now I'm not sure if I'm getting this correct, but if the second initiation site is in a different reading frame, you get a whole new protein product from within the same nucleotide sequence. This indeed happens in many prokaryotes, but I cannot recall ...

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by biohazard
Wed Aug 19, 2009 6:05 am
 
Forum: Cell Biology
Topic: multiple initiation sites.
Replies: 5
Views: 98

multiple initiation sites.

... it but I am wondering if you could offer some assistance or information on a web site. Q: What are the two major reasons fo the multiple initiation sites for eukaryotic replication? A: REASON #1: I think that there are multiple initiation sites so that synthesis can take place rapidly ...

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by NewtoBiology
Tue Aug 18, 2009 9:17 pm
 
Forum: Cell Biology
Topic: multiple initiation sites.
Replies: 5
Views: 98

Two questions about operon (transcription/translation)

I can't help you on 2, but for the first one, each gene has its own individual initiation site. If it didn't, each protein would connect into the other, and you'd have some gigantic, probably nonfunctioning protein. When one ends, the next starts

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by plasmodesmata11
Sun Aug 02, 2009 2:16 am
 
Forum: General Discussion
Topic: Two questions about operon (transcription/translation)
Replies: 2
Views: 109

Question for experts: Helicases

... In a human/eukaryotic cell, there are multiple origins of DNA replication. Helicases are part of the whole DNA synthesis initiation and elongation process. Using ATP, they are able to pull the base pairs apart from the SSB proteins that has "straightened out" ...

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by kolean
Sat Jul 04, 2009 11:03 pm
 
Forum: Molecular Biology
Topic: Question for experts: Helicases
Replies: 4
Views: 195
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