Endogenous

... cells. When infection occurs such as meningitis or encephalitis, because of the inflammation caused by bacterial toxins, destroyed neurons and endogenous substances, the endothelial cells become more permeable (the cell junctions loosen), and immune cells can enter the brain. Only lipo soluble ...

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... a pair of complementary mutagenic primers is used to amplify the entire plasmid. This generates a nicked, circular DNA which can undergo repair by endogenous bacterial machinery. However, this process does not amplify the DNA exponentially, rather, linearly. Yields are complicated by the fact that ...

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... can be an amplification step: after the RNA is exported into the cytoplasm, there can be an amplification of the signal by copying this RNA by an endogenous RNA-dependent RNA polymerase, which will produce even more RNA molecules that are substrates for Dicer. But I think the actual RNAi enzymes ...

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... its function. While a Morpholino can prevent that expression, a coinjected rescue RNA is often present prior to the onset of transcription of the endogenous RNA. This inappropriately early expression can prevent rescue of the wild-type phenotype for many genes. Similarly, the location of endogenous ...

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... work, there are various reasons for this including that you are injecting a large amount of mRNA that is not translated in accordance with how the endogenous mRNA is produced and translated. So you are basically over-expressing which can itself cause abnormalities. Another way is to make a construct ...

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