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Deoxyribose

Definition

noun

(1) An aldopentose (i.e. a monosaccharide with five carbon atoms) derived from the pentose sugar ribose by the replacement of a hydroxyl group with a hydrogen atom at the 2 position, leading to the net loss of an oxygen atom (hence the name).

(2) The sugar component in the side chains of DNA, in contrast to the ribose in the side chains of RNA.


Supplement

Word origin: deoxy + ribose (sugar)
Related forms: deoxyribo-

Chemical formula: C6H10O4

Also called:

  • D-deoxyribose
  • 2-deoxyribose

Compare: ribose

Related terms:


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DMSO in PCR

... how is the mechanism? One mechanism that I can imagine is that DMSO is a relatively weak acid, so it readily destabilizes DNA by disturbing purine-deoxyribose bond, yielding apurinic acid. Is it true? Thanks. Victor Apriel

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by victor
Mon Jul 21, 2008 5:08 am
 
Forum: Molecular Biology
Topic: DMSO in PCR
Replies: 1
Views: 2976

"salt of DNA"

"We wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.)." As a non-scientific writer, when I ran across this quote I was a little confused. I know that DNA is an acid, I just can't figure out how salt got into the ...

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by steve9191
Thu May 29, 2008 11:35 pm
 
Forum: Molecular Biology
Topic: "salt of DNA"
Replies: 2
Views: 599

Re: A few questions about DNA and isolation/viscosity!

This pertains mostly to separations by phenol extraction. The ribose ring of RNA is susceptible to elimination/hydroysis reactions at high pH. The deoxyribose ring of DNA is much more stable toward base compared to RNA. At pHs above 7, both RNA and DNA partition into the aqueos phase of a phenol ...

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by blcr11
Thu Apr 10, 2008 4:42 pm
 
Forum: Molecular Biology
Topic: A few questions about DNA and isolation/viscosity!
Replies: 3
Views: 595

In 3' and 5' what does the single quote mean?

OK, If you look Here (http://homepages.ius.edu/GKIRCHNE/DNA.htm) about half way down the page is an image with the numbers on the deoxyribose showing how it works.

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by BioLad
Wed Dec 05, 2007 2:45 am
 
Forum: Molecular Biology
Topic: In 3' and 5' what does the single quote mean?
Replies: 7
Views: 598

In 3' and 5' what does the single quote mean?

3' is the number 3 carbon and 5' is the number 5 carbon as you count on the deoxyribose.

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by BioLad
Wed Dec 05, 2007 2:40 am
 
Forum: Molecular Biology
Topic: In 3' and 5' what does the single quote mean?
Replies: 7
Views: 598
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