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Consensus sequence

Consensus sequence

Of a series of related dna, rna or protein sequences, the sequence that reflects the most common choice of base or amino acid at each position. Areas of particularly good agreement often represent conserved functional domains. The generation of consensus sequences has been subjected to intensive mathematical analysis.


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Sequencing

... overlap, given enough copies you should be able to build a contiguous consensus based on overlaps. Theoretically you could have a bunch of frags as short as 4bps long and still be able to get a decent length of sequence.

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by mith
Fri Apr 17, 2009 5:03 pm
 
Forum: Bioinformatics
Topic: Sequencing
Replies: 5
Views: 638

Re: Brain size=IQ level theory (Blacks vs Whites & Asians)

... Allen B.P. (2006). If No “Races,” No Relevance to Brain Size, and No Consensus on Intelligence, Then No Scientific Meaning to Relationships Among ... Z., John P, Ali G., Chishti M.S. and Ahmad W. Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive ...

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by bluecafe669
Tue Apr 15, 2008 12:50 am
 
Forum: Human Biology
Topic: Brain size=IQ level theory (Blacks vs Whites & Asians)
Replies: 18
Views: 12456

Regulatory elements of genes

Bioedit. There's also the operator, translation termination sequence and the stop codon, plus the consensus sequences at -10 and -35.

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by Sepals
Wed Mar 26, 2008 1:40 pm
 
Forum: Molecular Biology
Topic: Regulatory elements of genes
Replies: 3
Views: 488

Re: Can anyone help with this RNA question

If this is mRNA, why are there Ts in the sequence? This is supposed to represent the promoter region maybe? The promoter isn’t ... for example. There may not be (in fact, probably won't be) an exact fit to the consensus. I don’t think the Shine-Dalgarno sequence should be in this stretch of ...

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by blcr11
Wed Mar 12, 2008 3:35 pm
 
Forum: Molecular Biology
Topic: Can anyone help with this RNA question
Replies: 5
Views: 467

RNA nucleotides question

... question is somewhat confusing. The only GTA I see is in the coding sequence. If you delete the GTA, you have a three-base deletion. It doesn’t ... have anything to do with the Shine-Dalgarno sequence. In E. coli, the consensus Shine-Delgarno box is AGGAGGA. It’s function is to recruit and ...

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by blcr11
Mon Mar 10, 2008 1:40 pm
 
Forum: Molecular Biology
Topic: RNA nucleotides question
Replies: 1
Views: 352
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