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Dictionary » C » Conjugate

Conjugate

Definition

noun

The complex formed from the joining together of two or more molecules, especially by covalent bond.

verb

(biology) To undergo conjugation.

(immunology) To link marker protein to an antibody molecule in order to detect an antigen.

adjective

(botany) (of a pinnate leaflet) Having only one pair of leaflets.

(chemistry) Relating to a compound formed depending upon the loss or gain of a proton, as in a conjugate base or a conjugate acid.

(general) Joined together in pair(s); paired; coupled.


Supplement

Word origin: Latin coniugāre, coniugāt-, to join together : com-, com- + iugāre, to join.
Related forms: conjugation (noun)

Related terms:


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Re: is it possible to knockdown a gene in a living adult now

Here we go -- the first clinical trial with a Morpholino-peptide conjugate. http://www.bioresearchonline.com/article.mvc/AVI-BioPharma-Announces-Initiation-Of-0001 Start of press release: AVI BioPharma Announces Initiation Of Clinical Trial ...

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by jonmoulton
Tue Nov 18, 2008 6:05 pm
 
Forum: Genetics
Topic: is it possible to knockdown a gene in a living adult now
Replies: 10
Views: 1509

Re: is it possible to knockdown a gene in a living adult now

... JN, Youngblood DS, Iversen PL. Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide-Morpholino Oligomer Conjugate. Bioconjug Chem. 2007 Jun 21; [Epub ahead of print] Fletcher S, Honeyman K, Fall AM, Harding PL, Johnsen RD, Steinhaus JP, Moulton HM, Iversen ...

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by jonmoulton
Fri Nov 07, 2008 3:44 pm
 
Forum: Genetics
Topic: is it possible to knockdown a gene in a living adult now
Replies: 10
Views: 1509

possible peptide formation and ratio of acid to base

... acids? -is this a simple 15^20 caluclation or am I overlooking something. 15^20 = 3.3*10^23. This number seems quiet large. Calculate the ratio of conjugate base to acid form for each of the ionizable groups of glutamic acid in a medium of pH 4.0 -when calculating the ionizable groups of a amino ...

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by agw1200
Fri Oct 03, 2008 7:58 pm
 
Forum: Molecular Biology
Topic: possible peptide formation and ratio of acid to base
Replies: 2
Views: 631

biochemistry for dummies (me, that is...)

The Henderson-Hasselbach Equation relates the pH of a solution to the pKa of the acid and the ratio of the concentrations of conjugate base to its acid. Here, ionized aspirin is the conjugate base of the unionized, acidic form of aspirin. pH = pKa + log([ionized aspirin]/[unionized aspirin]) ...

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by blcr11
Sun Sep 07, 2008 11:27 am
 
Forum: Molecular Biology
Topic: biochemistry for dummies (me, that is...)
Replies: 8
Views: 3340

Preparing a Buffer Solution

... weight of 210.3grams. The pKa for the mops zwitter ion is 7.2. Now my question is...what exactly is the zwitter ionic form of mops...is that the conjugate base of the mops acid? And if it is the conjugate base would you need to convert some of it to the acid to get the buffer?...because a buffer ...

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by Elinor
Sun Sep 07, 2008 12:12 am
 
Forum: Molecular Biology
Topic: Preparing a Buffer Solution
Replies: 1
Views: 1873
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