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Dictionary » C » Cell differentiation

Cell differentiation

Definition

noun

The normal process by which a less specialized cell develops or matures to possess a more distinct form and function.


Supplement

For example, a single-celled zygote develops into a multicellular embryo that further develops into a more complex multisystem of distinct cell types of a fetus. The cell size, shape, polarity, metabolism and responsiveness to signals change dramatically such that a less specialized cell becomes more specialized and acquires a more specific role.


Variant: cellular differentiation.

Compare: dedifferentiation.


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Stem and Progenitor Cell Questions

I shall try to answer. 1. Stem cells are totipotent in that they can be made to be any cell in the organism. Totipotent ... the 4 cells and they will form 4 perfect organisms. After the 4 cell stage, differentiation of the cell has begun and the cells when pulled apart will follow only ...

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by kolean
Wed Sep 02, 2009 11:08 pm
 
Forum: Cell Biology
Topic: Stem and Progenitor Cell Questions
Replies: 2
Views: 24

multiple initiation sites.

... are being attached and preparing the chromatin for the rest of the cell cycle. The chromatin modeling proteins prepare the cell to keep its differentiation and thus epigenetic expression, upon replication.

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by kolean
Thu Aug 20, 2009 2:42 am
 
Forum: Cell Biology
Topic: multiple initiation sites.
Replies: 5
Views: 95

Anti-metastasis and Cytostasis, Differentiation between the

... was because of the anti-metastatic activity of the compounds, but not because of the cytostatic nature. I am currently using the C6, rat glioma cells and HeLa, human cervical cancer cells to perform the experiment. I have used MTT assay to determine the cytotoxicity of the compounds on the same ...

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by Gemini
Fri Jul 17, 2009 3:40 pm
 
Forum: Cell Biology
Topic: Anti-metastasis and Cytostasis, Differentiation between the
Replies: 0
Views: 163

Re: ?{REGENERATION}? Is it possible ???!!

Can you clarify the distinction between "transdifferentiation" and the "dedifferentiation and then differentiation" ... basically, are they not both repressing the phenotypic expression of one cell and transforming it into the phenotypic expression of another cell?

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by kolean
Mon Jun 29, 2009 1:42 pm
 
Forum: Cell Biology
Topic: ?{REGENERATION}? Is it possible ???!!
Replies: 31
Views: 1639

?{REGENERATION}? Is it possible ???!!

... like you to be right, but i fear that the more we look at in vivo dedifferentiation followed by differentiation into another cell type we see that it might not be a viable treatment option. right now it seems to me that ...

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by MrMistery
Sun Jun 28, 2009 5:17 pm
 
Forum: Cell Biology
Topic: ?{REGENERATION}? Is it possible ???!!
Replies: 31
Views: 1639
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