Acetyl

... because of essential oxygen supplies the reaction can continue inside the mitochondria. When pyruvate enters the mitochondria it is oxidized into Acetyl CoA producing 2NADH and 2CO2. This is the starting point for the Krebs Cycle. During the Krebs Cycle Acetyl CoA is bound to Oxaloacetate which ...

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... of histidine in fuel metabolism??? So far I haven't found any roles specific to histidine. Just things that are standard like transamination into acetyl Co-A. I know this is long winded but any help would be greatly appreciated. Thanks, J

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There's a lot going on with the conversion of pyruvate to acetyl-CoA to citrate reactions. That there is no net change in CoA just reflects the fact that it's part of the catalyst and catalysts by definition are regenerated and left unchanged by the process ...

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Here is what I think: the CoA attaches to the acetate and produces acetyl CoA; it isn't stable and makes it very reactive that it binds with the oxaloacetate in the Krebs cycle. CoA-SH then falls off and is free to bind with another acetate in order to bind ...

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... pathways. For example, AMP regulates fatty acid synthesis and catabolism by controlling availability of malonyl-CoA." "Regulation of Acetyl-CoA Carboxylase by local metabolites: * Palmitoyl-CoA, the product of Fatty Acid Synthase, promotes the inactive conformation of Acetyl-CoA Carboxylase ...

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