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Bacteriophage QuestionModerator: BioTeam
14 posts • Page 2 of 2 • 1, 2
I guess NOTHi,
Lets say one somehow managed to get a bacteriophage inside a human cell. In order for a bacteriophage (any virus for that matter) to "infect" a human cell it must be able to replicate its DNA inside the human cell. DNA replication involves many stages - intiation, elongation and termination. Each of these require specific activator proteins and most importantly some enzymes to do the job. Inside an E.Coli, DNA Polymerase I and III do the job of DNA replication. A bacteriophage exploits this host bacterium machinery to get its DNA replicated. But the human DNA replicase wont be able to replicate the phage replicon. Know thyself.
14 posts • Page 2 of 2 • 1, 2
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