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antibody

Postby janekelly on Thu Jan 24, 2008 12:49 am

why is it possible for us to survive with just one class of antibody?
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Postby mith on Thu Jan 24, 2008 3:02 am

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Re: antibody

Postby yongjj on Thu Jan 24, 2008 2:49 pm

I don't think we can survive with just one class of antibody.
Do you mean isotypes? We have 5 isotypes of antibodies. IgA, IgD, IgE, IgG and IgM. Please clarify your question.
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Postby victor on Fri Jan 25, 2008 4:42 am

yup, I think that Jenniferboateng06 refers to those isotypes. Hmm....I can say yes (even though the chance is so little and won't last long), because fetus only have one type of antibody which is IgG. And as far (or near) as I know that IgG is the most 'sensitive' antibody which really plays a role in immune system because it has a highest affinity towards matched antigen compared to another Ig families.
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Re: antibody

Postby janekelly on Sun Jan 27, 2008 6:28 pm

sorry, yh i did mean isotypes
yongjj wrote:I don't think we can survive with just one class of antibody.
Do you mean isotypes? We have 5 isotypes of antibodies. IgA, IgD, IgE, IgG and IgM. Please clarify your question.
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Postby DoctorStein on Fri May 30, 2008 11:13 am

Each antibody has its own function. For instance, IgA traps antigens on mucosal surface, IgE takes part against allergen, IgG will do surveillance all over the body, etc. We cannot rely only on one isotype of antibody.
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Postby MrMistery on Fri May 30, 2008 9:34 pm

No, but we can survive with only one isotype. For example, an immunocompromised person receiving an IVIG lives on...
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Postby DoctorStein on Sat May 31, 2008 2:11 am

Yes but it is not normal condition.
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Postby MrMistery on Sat May 31, 2008 6:41 pm

No, it's not, and neither did I say it was. That person would definitely not be as healthy as a person with a normal immune system but he would survive.
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Postby DoctorStein on Sun Jun 01, 2008 7:30 am

Well, if it is so, then, we can live WITHOUT any Ig available too ;)
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Postby MrMistery on Sun Jun 01, 2008 5:00 pm

for a day or two maybe, but not for long...
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Postby DoctorStein on Tue Jun 03, 2008 10:47 am

There is a child who lives without any Igs for a month or so... The clue is not the time or how long, but rather the presence of pathogenic ags.
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