How do we die?

[physiol_1]

I think, death is not due to apoptosis. B'coz all cells do not die immediately after death of a man.

[Poison]

I think, death is not due to apoptosis. B'coz all cells do not die immediately after death of a man.

Apoptosis is the programmed death of a CELL not the organism. It can happen anytime. And another thing is, people die from cancer and ,you know, cancer cells don't go through apoptosis.
The answer of the reason of death can be DNA. because you are programmed to live that long. Telomere can be an answer.

[sachin_vch]

Not Apoptosis only
Apptss is part of process of death.
Natural Death(accidental death is ultimately leads Natural Dth) Starts lot before the day of daeth.

Its In Your DNA.

Know Think.......

[Dr.Stein]

I just read a book about "Aging, Dying, and Death" It is stated that the death is started when brain cells are undergoing irreversible damaged. This can be caused by trauma e.g. from accidents or because lack of oxygen supply because of the weaken body system (blood circulatory system).

There are some cases that individuals still alive or back alive after heart resurcitation. This is because the damaged area of the brain is still little and the oxygen supply is still adequate.

In a special case, an individual is kept alive by life-supporting equipments. When those equipments are removed, the individual will be pass away. The possibility that the individual will come back alive (biologically alive) is very little. If it can be, usually the individual will live abnormal because of the brain damaged.

[G-Do]

The answer of the reason of death can be DNA. because you are programmed to live that long. Telomere can be an answer.

That's a little too simple. There isn't enough evidence yet to say that telomere attrition is a major cause of organismal death, or even cell death. Certainly, there is a correlation between telomere length and cell age in some animals, but that doesn't imply a causal link between them. Shortened telomeres can lead to the recognition of DNA double-strand breaks, which - in some circumstances - activates the pro-apoptotic machinery. However, in many other cases it activates the pro-senescence machinery, which keeps the cell alive, albeit in an altered, senescent state. How often the cell apoptoses vs senesces depends on the cell type and tissue microenvironment, and it is unclear what effect these per-cell decisions have on the organism as a whole. So it is a stretch to say that our telomeres constitute a genetic program for our deaths.

What's more, telomere attrition and the subsequent expression of senescence genes may actually give an edge to pro-survival factors! There is an idea floating around that when glandular cells (mammary gland, prostate gland) enter senescence, they begin to secrete hormones and growth factors inappropriately. These pro-survival, pro-growth factors swim around in the extracellular environment, causing other non-senescent cells to become tumorigenic. This is one explanation for why tissue age seems to be a more potent factor in the development of glandular cancers (breast cancer, prostate cancer) than other cancers.

[loveangel]

@dr. stein
who's the author of the book????

how do this prove that dna is responsible for death??? are there experiments being made to this?

[druid]

I think to answer "why do we die?" we need to answer first "why do we live?"
Right, reproduce.
Evolution has to worry only about life span that is enof to give offspring.
If the life span has been adjusted correctly, selfish gene will throw its shell, i.e. your body, by just not-repairing damages, giving entropy to terminate you.

[Dr.Stein]

@dr. stein
who's the author of the book????

how do this prove that dna is responsible for death??? are there experiments being made to this?

Damn, I forgot. I will write it when i got the book back

[loveangel]

okay, i'll be waiting for that! thanks in advance doc.

[Mr Joe]

i think i read this somewhere, not sure tho but it came to mind when i read the name of the post so here it is.............our body is calibrated to complete cell division a certain number of times when we reach that number and our body STOPS dividing cells thats when we die (of course we also die because of illness and injuries BUT considering we were healthy )

[MrMistery]

i sincerely doubt that.....

[Mr Joe]

oh well thought id give it a shot anyway lol