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DNA Gyrase vs. DNA Helicase

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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DNA Gyrase vs. DNA Helicase

Postby jayson on Tue Nov 29, 2005 2:10 am

What is the difference between the two ? (not structurelly (sp?), but by function)

Thanks in advance.
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Postby sdekivit on Tue Nov 29, 2005 8:58 pm

DNA gyrase produces DNA supercoiling and DNA helicase unwinds DNA
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Postby jayson on Tue Nov 29, 2005 8:58 pm

Doesn't Gyrase also relive the tension from the DNA strand.
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Postby Jennifer on Wed Nov 30, 2005 1:37 am

DNA helicase unwinds the double helix by disrupting the hydrogen bonds of the base pairs of nucleotides. DNA gyrase relieves the tension from the unwinding of the double helix by cutting the strand, and reannealing it once the tension has been released.
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Postby sdekivit on Wed Nov 30, 2005 3:32 pm

NOOOOOOO!!!!!! DNA gyrase = DNA topoisomerase II and produces negative supercoils

--> DNA topoisomerase I relaxes these negative supercoils.

DNA helicase pulls the DNA strands away from each other for transcription and is completely different from producing/relaxing supercoils
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