mRNA

[Jennifer]

Can anyone tell me the destiny of mRNA after it has been used to code for protein? I know that the nucleotides are reused, but I have to be really specific!
Any help would be awesome!

[jayson]

I think they get digested by the enzymes in the cytoplasm. That is why they add the poly-a-tail to the 3' end, to prevent the digestion of the codons.

[sdekivit]

Can anyone tell me the destiny of mRNA after it has been used to code for protein? I know that the nucleotides are reused, but I have to be really specific!
Any help would be awesome!

i think the mRNA is ubiquitinated and degraded in the proteasome.

[Jennifer]

Thanks!

[cool A-level student]

mRNA or messenger RNA is a single strand of copied DNA which ends up at the ribosomes where it is changed into amino acids and thus proteins using the instructions from the mRNA.

mRNA is made so that its not all "messy" in the cell with all the DNA going everywhere, so mRNA is copied to give a small part of instructions to where it is needed without being messy
neat huh?

[MrMistery]

I don't remember how it works actually, but the same mRNA molecule codes for the same protein many times before it is degraded by enzimes. What i don't remember is how the cell decides if it needs more protein or not. probably some receptor that stimulates the recycling of cAMP for protease synthesis or something...

[nick4106]

It is degraded by proteasomes in the cell. They degrade used and misfolded proteins into 7-9aa strands.