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Biology Articles » Toxicology » Neurotoxic Effects of Gasoline and Gasoline Constituents » Introduction

Introduction
- Neurotoxic Effects of Gasoline and Gasoline Constituents

This overview was developed as part of a symposium on noncancer end points of gasoline and key gasoline constituents. The specific constituents included in the overview are methyl tertiary butyl ether, ethyl tertiary butyl ether, tertiary amyl methyl ether, butadiene, benzene, xylene, toluene, methyl alcohol, and ethyl alcohol. The overview is not meant to serve as an exhaustive review of the literature for all compounds. Instead, certain examples of the neurotoxic effects reported for each compound are included in the context of a discussion of a dose-response analysis or calculation of a no-observable-adverse-effect level (NOAEL) for human neurotoxic effects due to chronic lowlevel occupational or environmental exposure. Finally, the overview does not include studies of chemical mixtures other than gasoline. The focus for this overview is on specific key components of gasoline.


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