The present study was carried out to further examine the immune responses …

• Abstract
• Background
• Materials and methods
• Results
• Discussion
• References
• Figures

Biology Articles » Immunobiology » Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction » Figures

Figures

- Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction

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Figure 1 Body weight at sacrifice (upper panel) and clinical evolution of EAE in control and 33% and 66% calorie-restricted rats (lower panel). Male Lewis rats were kept for 1 month under a control or restricted diet, as described in Materials and methods. On day 15 the rats received complete Freund's adjuvant plus spinal cord homogenate (SCH) or complete Freund's adjuvant alone. Rats were assessed daily for clinical signs of EAE using the clinical criteria described in Materials and methods. Data shown as mean ± SEM. Upper panel: numbers designate the groups whose means differed significantly in a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p b p c p

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Figure 2 Mitogenic responses to Con A and LPS in spleen (left panels) and SmLN (right panels) of control and calorie-restricted rats. Data shown as mean ± SEM (n = 7 rats/group). Letters indicate the existence of significant differences between groups after a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p b p

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Figure 3 Relative size distributions of lymph cells in the spleen of control and calorie-restricted rats. CD4⁺, CD8⁺, CD4⁺-CD8⁺, T, B and T-B lymphocytes, as well as CD4⁺/CD8⁺ and T/B ratios, were measured as described in Materials and methods. Data shown as mean ± SEM (n = 7 rats/group). Letters indicate the existence of significant differences between groups after a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p b p c p d p e p f p g p h p

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Figure 4 Relative size distributions of lymph cells in SmLN of control and calorie-restricted rats. CD4⁺, CD8⁺, CD4⁺-CD8⁺, T, B and T-B lymphocytes, as well as CD4⁺/CD8⁺ and T/B ratios, were measured as described in Materials and methods. Data shown as mean ± SEM (n = 7 rats/group). Letters indicate the existence of significant differences between groups after a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p b p c p d p e p f p g p h p

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Figure 5 Relative size distributions of lymph cells in the thymus of control and calorie restricted rats. CD4⁺, CD8⁺, CD4⁺-CD8⁺, T, B and T-B lymphocytes, as well as CD4⁺/CD8⁺ and T/B ratios, were measured as described in Materials and methods. Data shown as mean ± SEM (n = 7 rats/group). Letters indicate the existence of significant differences between groups after a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p b p c p d p e p f p

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Figure 6 IFN-γ release from splenic, SmLN and thymic cells of control and calorie-restricted rats. Data shown as mean ± SEM (n = 7 rats/group). Letters indicate the existence of significant differences between groups after a one-way ANOVA followed by a Bonferroni's test, as follows: ^a p b p c p d p

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