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The authors reviewed the current thinking and progress on how to get …


Biology Articles » Bioinformatics » From genome to epigenome » Outlook

Outlook
- From genome to epigenome

OUTLOOK 

While the discussion continues on what constitutes ‘the’ epigenome and how the underlying data can be integrated, international frameworks are now in place to make a start on those epigenetic data sets that can be defined and for which sufficiently mature technologies exist for genome-wide scale-up. DNA methylation profiling clearly has reached that stage and is likely to provide us the first glimpse into an epigenome, similar to EST sequences that provided the first view into the human genome. Considering the current excitement surrounding the epigenome, completion of the HEP is expected to be self-catalyzing and could happen before the end of this decade.


ACKNOWLEDGEMENTS  

A.M. and S.B. were supported by the Wellcome Trust and V.R. was supported by a C.J. Martin Fellowship from the National Health and Medical Research Council of Australia.



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