Anti-tumor immunity failure in mammals can be defined as an immunoreproductive phenomenon, …

• Abstract
• Introduction
• Basic mechanisms for the escape of tumors andTrophoblast from immune response
• Tumors in mammals and other classes ofVertebrates
• Conclusion
• References

Biology Articles » Evolutionary Biology » Failure of anti-tumor immunity inmammals - evolution of the hypothesis » Conclusion

Conclusion

- Failure of anti-tumor immunity inmammals - evolution of the hypothesis

Observations about similarities of behavior and phenotype between tumor and embryonic/trophoblast cells are very old. Besides morphological and functional similarities, there is much evidence that immunological events in pregnancy and malignancy are closely connected or the same. This possibility enables the establishing of a new definition of anti-tumor immunity failure in mammals as an immunoreproductive phenomenon, as well as new possibilities for immunotherapy. Finally, the conclusion is that we can learn so much from our distant relatives.