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The authors presented an overview of different experimental and bioinformatic methods to …


Biology Articles » Bioinformatics » Experimental and bioinformatic approaches for interrogating protein–protein interactions to determine protein function » A collection of protein interaction database web sites

A collection of protein interaction database web sites
- Experimental and bioinformatic approaches for interrogating protein–protein interactions to determine protein function

A collection of protein interaction database web sites 

BIND, Biomolecular Interaction Network Database: http://www.bind.ca

DIP, Database of Interacting Proteins: http://dip.doe-mbi.ucla.edu/

PIM – Hybrigenics: http://pim.hybrigenics.com/pimriderext/common/index.jsp

PathCalling Yeast Interaction Database: http://portal.curagen.com/extpc/com.curagen.portal.servlet.Yeast

MINT, a Molecular Interaction Database: http://mint.bio.uniroma2.it/mint/

GRID, The General Repository for Interaction Datasets: http://biodata.mshri.on.ca/grid/servlet/Index

InterPreTS, Protein interaction prediction through tertiary structure: http://www.russell.embl.de/interprets/

STRING, predicted functional associations among gene/proteins: http://string.embl.de/

Mammalian protein–protein interaction database (PPI): http://fantom21.gsc.riken.go.jp/PPI/

InterDom, Database of putative interacting protein domains: http://interdom.lit.org.sg/

FusionDB, database of bacterial and archaeal gene fusion events: http://igs-server.cnrs-mrs.fr/FusionDB/

IntAct Project: http://www.ebi.ac.uk/intact/index.html

The Human Protein Interaction Database: http://wilab.inha.ac.kr/hpid/

ADVICE, Automated Detection and Validation of Interaction by Co-Evolution: http://advice.i2r.a-star.edu.sg/

InterWeaver, protein interaction reports with online evidence: http://interweaver.i2r.a-star.edu.sg/

PathBLAST, alignement of protein interaction networks: http://www.pathblast.org/bioc/pathblast/blastpathway.jsp

ClusPro, a fully automated algorithm for protein–protein docking: http://nrc.bu.edu/cluster/

HPRD, Human Protein Reference Database: http://www.hprd.org/


Funding 

This research was supported by the Canadian Institutes of Health Research. The authors declare that there is no conflict of interest that would prejudice the impartiality of this scientific work.



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