The present Houston Vanguard sub-study examines a small group of subcutaneously IL-2 (…

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• Abbreviations
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Biology Articles » Immunobiology » CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV » Conclusion

Conclusion

- CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV

These data suggest that examination of CD8⁺ T cell apoptosis might serve as an indirect measure of the ability to respond to immunoreconstitution. Our longitudinal univariate analyses showed that both age and annexin were significant predictors of CD4 T cell numbers over time. However, entry of race into the model, showed that annexin lost it's independent relationship to CD4+ T cell number over time. Examination of possible ethnic differences in response to immune reconstitution is therefore also warranted.