Bupivacaine versus lidocaine analgesia for neonatal circumcision
Orit C Stolik-Dollberg1 ,3 and Shaul Dollberg2 ,3
1Department of Anesthesiology, Sheba Medical Center, Tel Hashomer, Israel
2Department of Neonatology, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
3Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel
Background
Analgesia for neonatal circumcision was recently advocated for every male infant, and its use is considered essential by the American Academy of Pediatrics. We compared the post-operative analgesic quality of bupivacaine to that of lidocaine for achieving dorsal penile nerve block (DPNB) when performing neonatal circumcision.
Methods
Data were obtained from 38 neonates following neonatal circumcision. The infants had received DPNB analgesia with either lidocaine or bupivacaine. The outcome variable was the administration by the parents of acetaminophen during the ensuing 24 hours.
Results
Seventeen infants received lidocaine and 19 received bupivacaine DPNB. Ten infants in the lidocaine group (59%) were given acetaminophen following circumcision compared to only 3 (16%) in the bupivacaine group (P 2 = 20.6; P = 0.006).
Conclusion
DPNB with bupivacaine for neonatal circumcision apparently confers better analgesia than lidocaine as judged by the requirement of acetaminophen over the ensuing 24-hour period.
BMC Pediatrics 2005, 5:12. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.