This paper will provide some examples of misleading annotations with regard to …

• Abstract
• Introduction
• Proteins rich in particular amino acids
• Proteins having several biological activities
• Proteins containing several functional domains
• Conclusion
• Acknowledgements
• References

Biology Articles » Bioinformatics » Bioinformatics as a critical prerequisite to transcriptome and proteome studies

Abstract

- Bioinformatics as a critical prerequisite to transcriptome and proteome studies

Bioinformatics as a critical prerequisite to transcriptome and proteome studies

Elisabeth Jamet^*

Surfaces Cellulaires et Signalisation chez les Végétaux, UMR CNRS-UPS 5546, 24, chemin de Borderouge, BP 17 Auzeville, F-31326 Castanet Tolosan, France

^* Fax: +33 (0)5 62 19 35 02. E-mail: jamet@scsv.ups-tlse.fr

Large-scale genomic studies rely strongly on annotations available in databases to design experimental supports such as arrays or to explain results in term of biological meaning. Most of this information originates from bioinformatic predictions. Their accuracy as well as their relevance to existing biological data are critical in avoiding the misinterpretation of experimental results.

Key words: Bioinformatic predictions, biological data, database, genomic studies, interpretation of results

Source: Journal of Experimental Botany 2004 55(405):1977-1979.